The significance of Transportation, Environmental Pollution and Health Status cannot be overemphasized. The problem of Environmental Pollution has seemingly become intractable with the incessant failure of both global and local environment policies. The aim of this research is to study the impact of Travel Behavior and Environmental Pollution on Health Status of travelers in Ilorin West Local Government Area of Kwara State. Data were obtained from the respondents through a well-structured questionnaire, Descriptive statistics was used to analyze the objectives. The findings revealed that population of female respondents 52.8% is higher than that of male respondents which is 47.2% in the study area, it also shows that majority (73.0%) experienced form of pollution in their journey, 52.8% of the pollution where caused by exhaust from vehicles. The findings shows that most of the impact of air and noise pollution highly affect the health. Air and Noise pollution also caused discomfort in the life of the respondents. The study recommended that government should ensure emission standards for in-use vehicles be set at levels that are achievable by a majority of vehicles with good maintenance. Also, vehicles that are not fit for the road should be banned so as reduce human exposure to air pollution and adverse health impacts associated with these pollutants. Urban transportation policies, which emphasize accessibility, that is, reducing the need to travel, should be aimed.